Welcome to the Kovar Lab



Cells regulate actin filament assembly to drive a wide range of fundamental cellular processes such as division, establishing polarity, endocytosis, mating and motility. The focus of our research group is to determine the molecular biochemical mechanisms that govern how the model systems fission yeast (Schizosaccharomyces pombe) and nematode worm (Caenorhabditis elegans) coordinate actin assembly through diverse actin associated proteins. We utilize multiple techniques both in and out of live cells including genetics, fluorescence microscopy, biochemistry, biophysics and innovative single actin filament imaging assays (movie).